RRP1 antibody

Catalog No. ABIN1387011

Product Details anti-RRP1 Antibody

Target: RRP1 (Ribosomal RNA Processing 1 Homolog A (RRP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NNP1/RRP1 like protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RRP1

Target: RRP1 (Ribosomal RNA Processing 1 Homolog A (RRP1))

Alternative Name: NNP1 (RRP1 Products)

Synonyms: D21S2056E antibody, NNP-1 antibody, NOP52 antibody, RRP1A antibody, Nnp1 antibody, AL033305 antibody, AL033306 antibody, AU018604 antibody, ribosomal RNA processing 1 antibody, ribosomal RNA processing 1 homolog (S. cerevisiae) antibody, RRP1 antibody, Rrp1 antibody

Background:

Synonyms: NNP 1, NNP-1, NNP1, Nnp1 homolog nucleolar protein, Novel nuclear protein 1, Nucleolar protein Nop52, Protein NNP 1, Protein NNP1, Ribosomal RNA processing 1 homolog, Ribosomal RNA processing protein 1 homolog A, rrp1, RRP1 like protein, RRP1-like protein, RRP1_HUMAN, RRP1A.

Background: Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway.

Gene ID: 8568