TRIM36 antibody

Catalog No. ABIN1386956

Product Details anti-TRIM36 Antibody

Target: TRIM36 (Tripartite Motif Containing 36 (TRIM36))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM36 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRIM36/RNF98

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TRIM36

Target: TRIM36 (Tripartite Motif Containing 36 (TRIM36))

Alternative Name: RNF98 (TRIM36 Products)

Synonyms: wu:fj48f01 antibody, zgc:153447 antibody, zgc:63476 antibody, Haprin antibody, MGC81170 antibody, TRIM36 antibody, HAPRIN antibody, RBCC728 antibody, RNF98 antibody, D18Wsu100e antibody, haprin antibody, tripartite motif containing 36 antibody, tripartite motif containing 36 L homeolog antibody, tripartite motif-containing 36 antibody, trim36 antibody, trim36.L antibody, TRIM36 antibody, Trim36 antibody

Background:

Synonyms: Acrosome RBCC protein, E3 ubiquitin protein ligase TRIM36, E3 ubiquitin-protein ligase Trim36, Haprin, RBCC728, Ring finger protein 98, TRI36_HUMAN, TRIM 36, TRIM36, Tripartite mot containing 36, Tripartite mot containing protein 36, Tripartite mot protein 36, Tripartite mot-containing protein 36, Zinc binding protein Rbcc728, Zinc-binding protein Rbcc728.

Background: TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger, a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localizing to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilization. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.

Gene ID: 55521