RCBTB1 antibody
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- Target See all RCBTB1 Antibodies
- RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RCBTB1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RCBTB1/CLLD7
- Isotype
- IgG
- Top Product
- Discover our top product RCBTB1 Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))
- Alternative Name
- RCBTB1 (RCBTB1 Products)
- Synonyms
- fj43a07 antibody, zgc:56037 antibody, wu:fj43a07 antibody, MGC81035 antibody, rcbtb1 antibody, CLLD7 antibody, CLLL7 antibody, GLP antibody, RP11-185C18.1 antibody, 5430409I18Rik antibody, AW111883 antibody, RCC1 and BTB domain containing protein 1 antibody, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antibody, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 S homeolog antibody, RCC1 and BTB domain-containing protein 1 antibody, Rcbtb1 antibody, RCBTB1 antibody, rcbtb1 antibody, rcbtb1.S antibody, LOC100470400 antibody
- Background
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Synonyms: Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, CLLD7, CLLL7 protein, Guanine nucleotide exchange factor, broad-complex, tramtrack and bric a brac, Hypothetical protein FLJ39335, RCBT1_HUMAN, Rcbtb1, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1.
Background: The BTB domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. RCBTB1 (regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1), also known as GLP, CLLD7, CLLL7 or E4.5, is a 531 amino acid protein that localizes to the nucleus and contains two BTB (POZ) domains and six RCC1 repeats. Expressed ubiquitously, RCBTB1 is thought to be involved in cell cycle regulation, specifically via chromatin remodeling. The gene encoding RCBTB1 maps to a region on human chromosome 13 that is frequently deleted in B-cell chronic lymphocytic leukemia, suggesting a possible role for RCBTB1 in tumor suppression.
- Gene ID
- 55213
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