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OLIG1 antibody (AA 121-220)

OLIG1 Reactivity: Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386861
  • Target See all OLIG1 Antibodies
    OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reactivity
    • 33
    • 32
    • 25
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    Rat
    Host
    • 61
    • 3
    Rabbit
    Clonality
    • 60
    • 4
    Polyclonal
    Conjugate
    • 32
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OLIG1 antibody is un-conjugated
    Application
    • 59
    • 28
    • 12
    • 12
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human OLIG1
    Isotype
    IgG
    Top Product
    Discover our top product OLIG1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
    Alternative Name
    OLIG1 (OLIG1 Products)
    Synonyms
    OLIG1 antibody, BHLHB6 antibody, BHLHE21 antibody, AI836478 antibody, AW494459 antibody, Bhlhb6 antibody, Olg-1 antibody, Oligo1 antibody, bHLHe21 antibody, Olg1 antibody, oligodendrocyte transcription factor 1 antibody, OLIG1 antibody, Olig1 antibody
    Background

    Synonyms: Oligo 1, Oligo1, Oligodendrocyte lineage transcription factor 1, Oligodendrocyte specic bHLH transcription factor 1, Oligodendrocyte transcription factor 1. Basic domain helix loop helix protein class B 6, Basic domain helix loop helix protein class B6, BHLH B6, BHLHB 6, BHLHB6, bHLHe21, Class B basic helix-loop-helix protein 6, Class E basic helix-loop-helix protein 21, Olig 1, Olig1, OLIG1_HUMAN.

    Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

    Gene ID
    116448
    UniProt
    Q8TAK6
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