CASR antibody (AA 121-220)

Catalog No. ABIN1386858

Product Details anti-CASR Antibody

Target: CASR (Calcium-Sensing Receptor (CASR))

Binding Specificity: AA 121-220

Reactivity: Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Pig

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calcium Sensing Receptor/CaSR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CASR antibody (ABIN1386858)

Liu, Tan, Huang, Li, Wang, Liao, Guan, Ji, Yin: "Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation." in: The British journal of nutrition, Vol. 120, Issue 12, pp. 1321-1331, (2019) (PubMed).

Huang, Xiao, Tan, Xiao, Wang, Yin, Duan, Huang, Yang, Yin: "Chitosan Oligosaccharide Reduces Intestinal Inflammation That Involves Calcium-Sensing Receptor (CaSR) Activation in Lipopolysaccharide (LPS)-Challenged Piglets." in: Journal of agricultural and food chemistry, Vol. 64, Issue 1, pp. 245-52, (2016) (PubMed).

Target Details for CASR

Target: CASR (Calcium-Sensing Receptor (CASR))

Alternative Name: Calcium Sensing Receptor (CASR Products)

Background:

Synonyms: CAR, FHH, FIH, HHC, EIG8, HHC1, NSHPT, PCAR1, GPRC2A, HYPOC1, Extracellular calcium-sensing receptor, CaSR, Parathyroid cell calcium-sensing receptor 1

Background: Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Gene ID: 846

UniProt: P41180

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis