FBXO7 antibody (AA 251-350)

Catalog No. ABIN1386851

Product Details anti-FBXO7 Antibody

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBXO7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7 (FBXO7 Products)

Synonyms: fbxo7 antibody, MGC80085 antibody, FBXO7 antibody, fbx7 antibody, MGC135804 antibody, MGC145325 antibody, ATFBP7 antibody, F-BOX PROTEIN 7 antibody, F-box protein 7 antibody, F8K7.20 antibody, F8K7_20 antibody, DKFZp469H0739 antibody, si:ch211-286m4.2 antibody, zgc:114096 antibody, FBX antibody, FBX07 antibody, FBX7 antibody, PARK15 antibody, PKPS antibody, 2410015K21Rik antibody, A230052G17Rik antibody, AI117679 antibody, AW260462 antibody, C85118 antibody, F-box protein 7 antibody, F-box protein 7 L homeolog antibody, FBXO7 antibody, fbxo7.L antibody, fbxo7 antibody, FBP7 antibody, Fbxo7 antibody

Background:

Synonyms: F box only protein 7, F box protein 7, F-box protein 7, FBX, FBX07, FBX7, PARK15, PKPS,

Background: FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Gene ID: 25793