C1orf63 antibody (AA 4-100)

Catalog No. ABIN1386775

Product Details anti-C1orf63 Antibody

Target: C1orf63 (Chromosome 1 Open Reading Frame 63 (C1orf63))

Binding Specificity: AA 4-100

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf63 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NPD014

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-C1orf63 antibody (ABIN1386775)

Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." in: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

Target Details for C1orf63

Target: C1orf63 (Chromosome 1 Open Reading Frame 63 (C1orf63))

Alternative Name: NPD014 (C1orf63 Products)

Synonyms: NPD014 antibody, DJ465N24.2.1 antibody, RP3-465N24.4 antibody, DKFZp469M2120 antibody, arginine and serine rich protein 1 antibody, chromosome 1 open reading frame 63 antibody, RSRP1 antibody, C1orf63 antibody

Background:

Synonyms: NPD014, C1orf63, DJ465N24.2.1, Arginine/serine-rich protein 1, RSRP1, HT033

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf63 gene product has been provisionally designated C1orf63 pending further characterization.

Gene ID: 57035

UniProt: Q9BUV0