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GRM2 antibody

GRM2 Reactivity: Human, Rat, Mouse, Cow, Dog, Chicken IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386756
  • Target See all GRM2 Antibodies
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    Reactivity
    • 57
    • 53
    • 36
    • 15
    • 15
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Chicken
    Host
    • 66
    • 5
    • 1
    Rabbit
    Clonality
    • 63
    • 9
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GRM2 antibody is un-conjugated
    Application
    • 31
    • 23
    • 20
    • 13
    • 11
    • 9
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Chicken, Cow, Dog, Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GRM2/GLUR2
    Isotype
    IgG
    Top Product
    Discover our top product GRM2 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
    Alternative Name
    Metabotropic Glutamate Receptor 2 (GRM2 Products)
    Synonyms
    GLUR2 antibody, GPRC1B antibody, MGLUR2 antibody, mGlu2 antibody, 4930441L02Rik antibody, Gprc1b antibody, mGluR2 antibody, mGluR7 antibody, glutamate metabotropic receptor 2 antibody, glutamate receptor, metabotropic 2 antibody, GRM2 antibody, Grm2 antibody
    Background

    Synonyms: Glutamate Receptor Metabotropic 2, Gprc1b, AMPA selective glutamate receptor 2, GLUR 2, GLUR2, GLURB, Glutamate receptor metabotropic 2, Metabotropic Glutamate Receptor 2, GPRC1B, GRM 2, Grm2, mGlu 2, MGlu2, MGLUR 2, Mglur2, GRM2_HUMAN.

    Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

    Molecular Weight
    96kDa
    Gene ID
    2912
    Pathways
    cAMP Metabolic Process, Dicarboxylic Acid Transport
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