DDAH1 antibody (AA 201-285)

Catalog No. ABIN1386647

Product Details anti-DDAH1 Antibody

Target: DDAH1 (Dimethylarginine Dimethylaminohydrolase 1 (DDAH1))

Binding Specificity: AA 201-285

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDAH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDAH1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DDAH1

Target: DDAH1 (Dimethylarginine Dimethylaminohydrolase 1 (DDAH1))

Alternative Name: DDAH1 (DDAH1 Products)

Synonyms: DDAH antibody, 2410006N07Rik antibody, 2510015N06Rik antibody, AI987801 antibody, AW050362 antibody, DDAH1 antibody, wu:fc30c11 antibody, zgc:85829 antibody, dimethylarginine dimethylaminohydrolase 1 antibody, dimethylarginine dimethylaminohydrolase 1 L homeolog antibody, DDAH1 antibody, Ddah1 antibody, ddah1.L antibody, ddah1 antibody

Background:

Synonyms: DDAH, DDAH I, DDAH-1, DDAH1, DDAH1_HUMAN, DDAHI, Dimethylargininase 1, Dimethylargininase-1, Dimethylarginine dimethylaminohydrolase 1, NG, NG-dimethylarginine dimethylaminohydrolase 1, NG NG dimethylarginine dimethylaminohydrolase.

Background: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).

Gene ID: 23576

UniProt: O94760