SLITRK6 antibody (AA 201-300)

Catalog No. ABIN1386633

Product Details anti-SLITRK6 Antibody

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Binding Specificity: AA 201-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLITRK6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SLITRK6

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Alternative Name: SLITRK6 (SLITRK6 Products)

Synonyms: 4832410J21Rik antibody, Sltk6 antibody, SLIT and NTRK like family member 6 antibody, SLIT and NTRK-like family, member 6 antibody, SLITRK6 antibody, slitrk6 antibody, Slitrk6 antibody

Background:

Synonyms: 4832410J21Rik, MGC119595, MGC119596, MGC119597, OTTHUMP00000066012, SLIK6_HUMAN, SLIT and NTRK like family member 6, SLIT and NTRK like protein 6, SLIT and NTRK-like protein 6, Slit and trk like 6, Slit and trk like gene 6, SLITRK 6, Slitrk6.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic ?/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK6 (SLIT and NTRK-like family, member 6) is an 841 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in select brain tissue, as well as in both adult and fetal lung, SLITRK6 functions to suppress neurite outgrowth, playing a role in the regulation of neuronal function. Multiple isoforms of SLITRK6 exist due to alternative splicing events.

Gene ID: 84189

UniProt: Q9H5Y7