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NPDC1 antibody (AA 75-180)

NPDC1 Reactivity: Mouse WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386609
  • Target See all NPDC1 Antibodies
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Binding Specificity
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 75-180
    Reactivity
    • 28
    • 21
    • 7
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 32
    • 2
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPDC1 antibody is un-conjugated
    Application
    • 26
    • 12
    • 12
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NPDC1
    Isotype
    IgG
    Top Product
    Discover our top product NPDC1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Alternative Name
    NPDC1 (NPDC1 Products)
    Synonyms
    AI314472 antibody, NPDC-1 antibody, CAB antibody, CAB- antibody, CAB-1 antibody, CAB1 antibody, neural proliferation, differentiation and control, 1, gene 1 L homeolog antibody, neural proliferation, differentiation and control 1 antibody, neural proliferation, differentiation and control, 1 antibody, npdc1.1.L antibody, Npdc1 antibody, NPDC1 antibody
    Background

    Synonyms: AI314472, CAB1, Neural proliferation dferentiation and control protein 1, NPDC-1, NPDC1, NPDC1_HUMAN.

    Background: NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.

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