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NPAS3 antibody (AA 21-120)

NPAS3 Reactivity: Human ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386604
  • Target See all NPAS3 Antibodies
    NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivity
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 6
    Rabbit
    Clonality
    • 6
    Polyclonal
    Conjugate
    • 6
    This NPAS3 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NPAS3
    Isotype
    IgG
    Top Product
    Discover our top product NPAS3 Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    NPAS3 (Neuronal PAS Domain Protein 3 (NPAS3))
    Alternative Name
    NPAS3 (NPAS3 Products)
    Synonyms
    trh antibody, mop6 antibody, pasd6 antibody, MGC145768 antibody, MOP6 antibody, PASD6 antibody, bHLHe12 antibody, 4930423H22Rik antibody, neuronal PAS domain protein 3 antibody, npas3 antibody, NPAS3 antibody, Npas3 antibody
    Background

    Synonyms: Basic helix loop helix PAS protein MOP6, Basic-helix-loop-helix-PAS protein MOP6, bHLHe12, Class E basic helix-loop-helix protein 12, FLJ10003, FLJ11138, FLJ11605, Member of PAS protein 6, MOP 6, MOP6, Neuronal PAS domain containing protein 3, Neuronal PAS domain protein 3, Neuronal PAS domain-containing protein 3, Neuronal PAS3, NPAS 3, NPAS3, NPAS3_HUMAN, PAS domain-containing protein 6, PASD 6, PASD6.

    Background: The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2 and NPAS3, which are involved the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and may control regulatory pathways relevant to psychotic illness and to schizophrenia. It regulates tracheal cell fates in the embryo and is necessary for the development of the posterior spiracles and the salivary gland duct. NPAS3 contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. Efficient DNA binding by NPAS2 requires dimerization with another bHLH protein.

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