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NAB2 antibody (AA 221-320)

NAB2 Reactivity: Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386498
  • Target See all NAB2 Antibodies
    NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
    Binding Specificity
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    Reactivity
    • 44
    • 32
    • 26
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    Mouse
    Host
    • 41
    • 6
    Rabbit
    Clonality
    • 43
    • 4
    Polyclonal
    Conjugate
    • 26
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAB2 antibody is un-conjugated
    Application
    • 40
    • 10
    • 8
    • 7
    • 5
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NAB2
    Isotype
    IgG
    Top Product
    Discover our top product NAB2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
    Alternative Name
    NAB2/MADER (NAB2 Products)
    Synonyms
    mader antibody, AI451907 antibody, MADER antibody, NGFI-A binding protein 2 (EGR1 binding protein 2) antibody, Ngfi-A binding protein 2 antibody, NGFI-A binding protein 2 antibody, nab2 antibody, Nab2 antibody, NAB2 antibody
    Background

    Synonyms: EGR 1 binding protein 2, EGR-1-binding protein 2, EGR1 binding protein 2, MADER, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, MGC75085, Nab 2, nab2, NAB2_HUMAN, NGFI A binding protein 2 EGR1 binding protein 2, NGFI A binding protein 2, NGFI-A-binding protein 2, Protein MADER.

    Background: Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.

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