LSAMP antibody (AA 51-150)

Catalog No. ABIN1386409

Product Details anti-LSAMP Antibody

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSAMP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LSAMP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LSAMP

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Alternative Name: LSAMP (LSAMP Products)

Synonyms: chLAMP antibody, IGLON3 antibody, LAMP antibody, 5430428I19 antibody, AW046674 antibody, B130007O04Rik antibody, D930023J12Rik antibody, Lam antibody, Lamp antibody, limbic system-associated membrane protein antibody, LSAMP antibody, Lsamp antibody

Background:

Synonyms: IgLON family member 3, IGLON3, Lam, LAMP, Limbic system associated membrane protein, Limbic system associated membrane protein precursor, Limbic system-associated membrane protein, LSAMP, LSAMP_HUMAN.

Background: LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99 % sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas.