Olfactomedin 3 antibody (AA 101-200)

Catalog No. ABIN1386387

Product Details anti-Olfactomedin 3 Antibody

Target: Olfactomedin 3 (OLFM3)

Binding Specificity: AA 101-200

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Olfactomedin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OLFM3/Optimedin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Olfactomedin 3

Target: Olfactomedin 3 (OLFM3)

Alternative Name: OLFM3/Optimedin (OLFM3 Products)

Synonyms: MGC83418 antibody, MGC148672 antibody, olfm3 antibody, zgc:171621 antibody, NOE3 antibody, NOELIN3 antibody, NOELIN3_V1 antibody, NOELIN3_V2 antibody, NOELIN3_V3 antibody, NOELIN3_V4 antibody, NOELIN3_V5 antibody, NOELIN3_V6 antibody, OPTIMEDIN antibody, B230206G02Rik antibody, olfactomedin 3 antibody, olfactomedin 3 L homeolog antibody, olfactomedin 3a antibody, OLFM3 antibody, olfm3.L antibody, olfm3a antibody, Olfm3 antibody

Background:

Synonyms: Noe3, NOE3_HUMAN, Noelin 3, Noelin-3, NOELIN3, NOELIN3 V1, NOELIN3 V2, NOELIN3 V3, NOELIN3 V4, NOELIN3 V5, NOELIN3 V6, Olfactomedin 3, Olfactomedin related ER localized protein 3, Olfactomedin-3, Olfactomedin3, Olfm3, Optimedin.

Background: OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.