RP1 antibody (AA 451-550)
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- Target See all RP1 Antibodies
- RP1 (Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
- Binding Specificity
- AA 451-550
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RP1 antibody is un-conjugated
- Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RP1/Oxygen-regulated protein 1
- Isotype
- IgG
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- RP1 (Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
- Alternative Name
- Oxygen-regulated protein 1 (RP1 Products)
- Synonyms
- orp1 antibody, MGC83581 antibody, DCDC4A antibody, ORP1 antibody, Rp1h antibody, Dcdc3 antibody, Orp1 antibody, mG145 antibody, RP1, axonemal microtubule associated L homeolog antibody, RP1, axonemal microtubule associated antibody, retinitis pigmentosa 1 (autosomal dominant) antibody, uncharacterized LOC100355685 antibody, retinitis pigmentosa 1 (human) antibody, rp1.L antibody, RP1 antibody, rp1 antibody, LOC100355685 antibody, Rp1 antibody
- Background
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Synonyms: DCDC4A, ORP1, Oxygen-regulated protein 1, Retinitis pigmentosa 1 protein, Retinitis pigmentosa RP1 protein, RP1, RP1_HUMAN.
Background: Retinitis pigmentosa 1 is a novel 2,156 amino acid oxygen-regulated photoreceptor specific to retina. Originally named ORP1 (for 'oxygen-regulated protein-1'), the expression of retinitis pigmentosa 1 has been found to be regulated by oxygen levels in the retina. Mutation of the retinitis pigmentosa 1 gene causes dominant retinitis pigmentosa which leads to degeneration of retinal photoreceptor cells and symptoms such as night vision blindness and deficits in the midperipheral visual field. Retinitis pigmentosa 1 may assist in differentiation of photoreceptor cells and has been identified in the cilia of photoreceptors, possibly aiding in both cilial structure and protein transport between inner and outer segments of photoreceptors. Retinitis pigmentosa 1 contains two doublecortin domains and is encoded by a gene which maps to human chromosome 8q11-q13.
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