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Transferrin Receptor antibody (AA 621-720)

Name: Transferrin Receptor antibody (AA 621-720)
SKU: ABIN1386360
Price: 384.62 USD
Availability: InStock

TFRC Reactivity: Human, Mouse FACS, WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

Mouse placenta lysates probed with Rabbit Anti-Transferrin receptor Polyclonal Antibody, Unconjugated at 1:500 for 90 min at 37˚C (Transferrin Receptor antibody (AA 621-720))

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CD71/TFR/Transferrin Polyclonal Antibody, Unconjugated (ABIN1386360) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (Transferrin Receptor antibody (AA 621-720))

IHC

Raji cells probed with Transferrin receptor Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (Transferrin Receptor antibody (AA 621-720))

FACS

Image provided by One World Lab validation program. (Transferrin Receptor antibody (AA 621-720))

IF (cc)

4 images

Catalog No. ABIN1386360

Datasheet as PDF

Target See all Transferrin Receptor (TFRC) Antibodies

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
Binding Specificity
15

14

11

8

8

7

6

6

6

5

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 621-720
Reactivity
192

82

26

7

5

4

2

2

2

1

1

1

1
Human, Mouse
Host
111

103

29

1

1
Rabbit
Compatible Secondaries
Clonality
144

99

1
Polyclonal
Conjugate
107

27

21

14

10

5

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Transferrin Receptor antibody is un-conjugated
Application
139

133

72

70

49

37

23

19

17

12

7

6

3

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity

Human, Mouse

Predicted Reactivity

Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Transferrin receptor

Isotype

IgG

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TFRC Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal MEM-75 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibody
TFRC Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibody
TFRC Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)
TFRC Reactivity: Human FACS, IP, ICC Host: Mouse Monoclonal MEM-75 Biotin

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 649-677), (C-Term) antibody
TFRC Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB20736 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 608-727) antibody
TFRC Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1A1B2 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibody
TFRC Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1E6 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Target

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name

Transferrin receptor (TFRC Products)

Synonyms

Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody

Background

Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC
Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Gene ID

7037

UniProt

P02786

Pathways

Transition Metal Ion Homeostasis