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MTPN antibody (AA 41-118)

MTPN Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386301
  • Target See all MTPN Antibodies
    MTPN (Myotrophin (MTPN))
    Binding Specificity
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 41-118
    Reactivity
    • 24
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 4
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTPN antibody is un-conjugated
    Application
    • 25
    • 12
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Myotrophin/GCDP
    Isotype
    IgG
    Top Product
    Discover our top product MTPN Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MTPN (Myotrophin (MTPN))
    Alternative Name
    Myotrophin/GCDP (MTPN Products)
    Synonyms
    MGC76285 antibody, GCDP antibody, V-1 antibody, Gcdp antibody, wu:fa10f07 antibody, zgc:64078 antibody, 5033418D15Rik antibody, V1 antibody, myotrophin antibody, myotrophin S homeolog antibody, mtpn antibody, MTPN antibody, Mtpn antibody, mtpn.S antibody
    Background

    Synonyms: FLJ31098, FLJ99857, GCDP, Granule cell dferentiation protein, MTPN, MTPN_HUMAN, Myotrophin, Protein V 1, Protein V-1, V 1, MTPN_HUMAN.

    Background: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.

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