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Carkd antibody

Carkd Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386254
  • Target See all Carkd Antibodies
    Carkd (Carbohydrate Kinase Domain Containing (Carkd))
    Reactivity
    • 19
    • 19
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Carkd antibody is un-conjugated
    Application
    • 18
    • 12
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CARKD
    Isotype
    IgG
    Top Product
    Discover our top product Carkd Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Carkd (Carbohydrate Kinase Domain Containing (Carkd))
    Alternative Name
    CARKD (Carkd Products)
    Synonyms
    FLJ10769 antibody, DKFZp469O2314 antibody, LP3298 antibody, 0710008K08Rik antibody, 2810407E01Rik antibody, RGD1562691 antibody, NAD(P)HX dehydratase antibody, ATP-dependent (S)-NAD(P)H-hydrate dehydratase antibody, similar to S. cerevisiae YKL151C antibody, NAXD antibody, naxd antibody, Naxd antibody, R107.2 antibody, CaO19.11002 antibody
    Background

    Synonyms: Carbohydrate kinase domain containing, carbohydrate kinase domain-containing protein, FLJ10769, LP3298, NNRD_HUMAN.

    Background: CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

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