TRIM39 antibody

Catalog No. ABIN1386250

Product Details anti-TRIM39 Antibody

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM39 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF23

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TRIM39

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Alternative Name: RNF23 (TRIM39 Products)

Synonyms: TRIM39.2 antibody, MGC78802 antibody, TRIM39 antibody, DKFZp459K1530 antibody, RNF23 antibody, TFP antibody, TRIM39B antibody, RPP21 antibody, 1100001D15Rik antibody, E130103K13Rik antibody, RBCC-B30.2 antibody, Rnf23 antibody, mKIAA4179 antibody, tfp antibody, tripartite motif containing 39.2 antibody, tripartite motif containing 39 L homeolog antibody, E3 ubiquitin-protein ligase TRIM39 antibody, tripartite motif containing 39 antibody, tripartite motif-containing 39 antibody, TRIM39.2 antibody, trim39.L antibody, LOC100022234 antibody, trim39 antibody, TRIM39 antibody, LOC615278 antibody, Trim39 antibody

Background:

Synonyms: Ring finger protein 23, RNF23, Testis abundant finger protein, TFP, TFP RING FINGER PROTEIN 23, TRIM39, Tripartite mot containing 39, TRI39_HUMAN.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF23 (RING finger protein 23), also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1. Ubiquitously expressed and existing as two alternatively spliced isoforms, RNF23 is found at highest levels in spleen, testis, brain, kidney, liver, heart and skeletal muscle. RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, a short-lived, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, thereby facilitating apoptosis. RNF23 contains one B box-type zinc finger, a B30.2/SPRY domain and a single RING-type zinc finger.

Gene ID: 56658