TWF2 antibody (AA 51-150)

Catalog No. ABIN1386208

Product Details anti-TWF2 Antibody

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWF2/PTK9L

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TWF2

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Alternative Name: TWF2/PTK9L (TWF2 Products)

Synonyms: A6RP antibody, A6r antibody, PTK9L antibody, a6r antibody, a6rp antibody, ptk9l antibody, mstp011 antibody, A6-related antibody, AU014993 antibody, Ptk9l antibody, Ptk9r antibody, zgc:112092 antibody, MGC91817 antibody, twf2 antibody, Twf2 antibody, twf2-a antibody, twf2-b antibody, twinfilin actin binding protein 2 antibody, twinfilin actin-binding protein 2b antibody, twinfilin actin binding protein 2 L homeolog antibody, twinfilin-2 antibody, twinfilin actin-binding protein 2 antibody, twinfilin actin binding protein 2 S homeolog antibody, TWF2 antibody, twf2 antibody, Twf2 antibody, twf2b antibody, twf2.L antibody, LOC100724130 antibody, twf2.S antibody

Background:

Synonyms: A6 related protein, A6r, A6RP, hA6RP, MSTP011, Protein tyrosine kinase 9 like, PTK 9L, PTK9L,PTK9L, PTK9L protein tyrosine kinase 9 like, TWF 2, Twinfilin 1 like protein, Twinfilin 2, Twinfilin actin binding protein homolog 2, Twinfilin like protein, Twinfilin2, TWF2_HUMAN.

Background: Twinfilin-2 is a 349 amino acid protein that localizes to the perinuclear region of the cytoplasm, as well as to the cytoskeleton, and contains two ADF-H domains. Expressed ubiquitously, Twinfilin-2 functions as an Actin-binding protein that is able to both bind and sequester G-Actin and cap the barbed ends of Actin filaments, thereby inhibiting Actin polymerization and playing a role in Actin-related motile and morphological processes. Twinfilin-2 is subject to post-translational phosphorylation by PKC zeta. The gene encoding Twinfilin-2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Maintenance of Protein Location, Toll-Like Receptors Cascades