SOX12 antibody (AA 51-150)

Catalog No. ABIN1386043

Product Details anti-SOX12 Antibody

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX22

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX22/SOX12 (SOX12 Products)

Synonyms: SOX22 antibody, sox-k1 antibody, sox-k1-a antibody, sox33 antibody, xSox-33 antibody, xSox-K1 antibody, xSox33 antibody, 2010205A02Rik antibody, SRY-box 12 antibody, SRY box 12 antibody, SRY-box 12 S homeolog antibody, SRY (sex determining region Y)-box 12 antibody, SOX12 antibody, Sox12 antibody, sox12.S antibody

Background:

Synonyms: Homo sapiens SRY sex determining region Y box 12, Protein SOX-22, SOX 12, SOX 12 protein, SOX 22, SOX 22 protein, sox12, SOX12 protein, SOX12_HUMAN, SOX22 protein, SRY sex determining region Y box 12, SRY sex determining region Y box 22, SRY box 12, SRY box 22, SRY related HMG box gene 22, Transcription factor Sox-12.

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.