AAMDC antibody

Catalog No. ABIN1385961

Product Details anti-AAMDC Antibody

Target: AAMDC (Adipogenesis Associated Mth938 Domain Containing (AAMDC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AAMDC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11ORF67/PTD015

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AAMDC

Target: AAMDC (Adipogenesis Associated Mth938 Domain Containing (AAMDC))

Alternative Name: C11ORF67 (AAMDC Products)

Synonyms: C11orf67 antibody, C29H11orf67 antibody, c11orf67 antibody, zgc:112239 antibody, CK067 antibody, RGD1561459 antibody, 1810020D17Rik antibody, 1810037D19Rik antibody, LI2 antibody, adipogenesis associated Mth938 domain containing antibody, adipogenesis associated, Mth938 domain containing antibody, AAMDC antibody, aamdc antibody, Aamdc antibody

Background:

Synonyms: Chromosome 11 open reading frame 67, CK067, FLJ21035, Hypothetical protein LOC28971, MGC3367, PTD015, UPF0366 protein C11orf67, AAMDC_HUMAN.

Background: PTD015 is a 122 amino acid protein that belongs to the UPF0366 family. Existing as three alternatively spliced isoforms, the PTD015 gene is conserved in dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 11q14.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The PTD015 gene product has been provisionally designated PTD015 pending further characterization.

UniProt: Q9H7C9