C2orf47 antibody

Catalog No. ABIN1385958

Product Details anti-C2orf47 Antibody

Target: C2orf47 (Chromosome 2 Open Reading Frame 47 (C2orf47))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2orf47 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2ORF47

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C2orf47

Target: C2orf47 (Chromosome 2 Open Reading Frame 47 (C2orf47))

Alternative Name: C2ORF47 (C2orf47 Products)

Synonyms: C12H2orf47 antibody, C2orf47 antibody, chromosome 7 open reading frame, human C2orf47 antibody, matrix AAA peptidase interacting protein 1 antibody, matrix AAA peptidase interacting protein 1 L homeolog antibody, C7H2ORF47 antibody, MAIP1 antibody, maip1 antibody, maip1.L antibody

Background:

Synonyms: Chromosome 2 open reading frame 47, Hhypothetical protein LOC79568,

Background: C2orf47, also known as FLJ22555 or DKFZp666A212, is a 291 amino acid mitochondrial protein that is encoded by a gene located on human chromosome 2q33.1. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gene ID: 79568