GABRR2 antibody (AA 161-260)

Catalog No. ABIN1385890

Product Details anti-GABRR2 Antibody

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Binding Specificity: AA 161-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRR2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRR2

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GABRR2

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Alternative Name: GABRR2 (GABRR2 Products)

Synonyms: si:dkey-181i3.1 antibody, gamma-aminobutyric acid type A receptor rho2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, rho 2b antibody, gamma-aminobutyric acid type A receptor rho 2 subunit antibody, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2 antibody, gamma-aminobutyric acid receptor subunit rho-2 antibody, GABRR2 antibody, gabrr2b antibody, Gabrr2 antibody, LOC100653501 antibody

Background:

Synonyms: GABA receptor Rho 2 subunit, GABAA receptor, GABAA receptor subunit rho-2, GABAC receptor, GABRR 2, Gamma aminobutyric acid receptor rho 2 subunit [Precursor], Gamma-aminobutyric acid GABA A receptor, rho 2, Gamma-aminobutyric acid receptor subunit rho-2, Rho 2 GABA receptor, GBRR2_HUMAN.

Background: Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.