DSCAM antibody (AA 301-400)

Catalog No. ABIN1385879

Product Details anti-DSCAM Antibody

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Binding Specificity: AA 301-400

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSCAM antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Dscam

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DSCAM

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Alternative Name: Dscam (DSCAM Products)

Synonyms: CHD2-42 antibody, CHD2-52 antibody, Dscam antibody, DSCAM antibody, chd2-42 antibody, chd2-52 antibody, dscam antibody, GB15141 antibody, 4932410A21Rik antibody, 43Bc antibody, CG17800 antibody, CT39257 antibody, DScam antibody, DmDscam antibody, Dm_2R:13612 antibody, Dmel\\CG17800 antibody, Dscam-hv antibody, Dscam1 antibody, FBgn0033159 antibody, Neu1 antibody, dScam antibody, l(2)05518 antibody, l(2)43Bc antibody, p270 antibody, DS cell adhesion molecule antibody, Down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule a antibody, Down syndrome cell adhesion molecule 1 antibody, Down syndrome cell adhesion molecule-like protein Dscam2 antibody, down syndrome cell adhesion molecule antibody, Down syndrome cell adhesion molecule L homeolog antibody, DSCAM antibody, Dscam antibody, dscam antibody, dscama antibody, Dscam1 antibody, LOC5573626 antibody, CpipJ_CPIJ006173 antibody, dscam.L antibody

Background:

Synonyms: CHD2, CHD2-42, CHD2-52, Down syndrome cell adhesion molecule, DSCAM

Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Enhances netrin-induced phosphorylation of PAK1 and FYN. Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38.

Gene ID: 1826

UniProt: O60469

Pathways: Regulation of Cell Size