BEAN1 antibody (AA 10-70)

Catalog No. ABIN1385845

Product Details anti-BEAN1 Antibody

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Binding Specificity: AA 10-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BEAN1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BEAN1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BEAN1

Target: BEAN1 (Brain Expressed, Associated with NEDD4, 1 (BEAN1))

Alternative Name: BEAN1/SCA31 (BEAN1 Products)

Synonyms: BEAN antibody, SCA31 antibody, Bean antibody, brain expressed associated with NEDD4 1 antibody, brain expressed, associated with Nedd4, 1 antibody, BEAN1 antibody, Bean1 antibody

Background:

Synonyms: BEAN, Bean1, BEAN1_HUMAN, Brain-expressed protein associating with Nedd4 homolog, Protein BEAN1, SCA31.

Background: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].