C11orf46 antibody

Catalog No. ABIN1385813

Product Details anti-C11orf46 Antibody

Target: C11orf46 (Chromosome 11 Open Reading Frame 46 (C11orf46))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11orf46 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11ORF46

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C11orf46

Target: C11orf46 (Chromosome 11 Open Reading Frame 46 (C11orf46))

Alternative Name: C11ORF46 (C11orf46 Products)

Synonyms: MGC115732 antibody, ARF7EP antibody, C11orf46 antibody, dJ299F11.1 antibody, 2700007P21Rik antibody, 4930448O08Rik antibody, RGD1311463 antibody, C15H11orf46 antibody, ARL14EP antibody, ADP ribosylation factor like GTPase 14 effector protein L homeolog antibody, ADP ribosylation factor like GTPase 14 effector protein antibody, ADP-ribosylation factor-like 14 effector protein antibody, ADP-ribosylation factor like GTPase 14 effector protein antibody, arl14ep.L antibody, arl14ep antibody, ARL14EP antibody, Arl14ep antibody

Background:

Synonyms: Chromosome 11 open reading frame 46, DJ299F11.1, FLJ38968, Hypothetical protein LOC120534, Uncharacterized protein C11orf46, AL14E_HUMAN.

Background: C11orf46, also known as FLJ38968 or dJ299F11.1, is a 260 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gene ID: 120534