C22orf31 antibody

Catalog No. ABIN1385768

Product Details anti-C22orf31 Antibody

Target: C22orf31 (Chromosome 22 Open Reading Frame 31 (C22orf31))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C22orf31 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C22orf31

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C22orf31

Target: C22orf31 (Chromosome 22 Open Reading Frame 31 (C22orf31))

Alternative Name: C22orf31 (C22orf31 Products)

Synonyms: HS747E2A antibody, bK747E2.1 antibody, chromosome 22 open reading frame 31 antibody, C22orf31 antibody

Background:

Synonyms: HS747E2A, bK747E2.1, C22orf31, Chromosome 22 open reading frame 31, HS747E2A, Hypothetical protein LOC25770, CV031_HUMAN.

Background: C22orf31, also known as HS747E2A or bK747E2.1, is a 290 amino acid protein encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

Gene ID: 25770