GJC3 antibody

Catalog No. ABIN1385717

Product Details anti-GJC3 Antibody

Target: GJC3 (GJc3) (Gap Junction Protein, gamma 3, 30.2kDa (GJc3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Connexin 29

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GJC3

Target: GJC3 (GJc3) (Gap Junction Protein, gamma 3, 30.2kDa (GJc3))

Alternative Name: Connexin-29 (GJc3 Products)

Synonyms: Cx29 antibody, Gje1 antibody, CX29 antibody, CX30.2 antibody, CX31.3 antibody, GJE1 antibody, gap junction gamma-3 protein antibody, gap junction protein, gamma 3 antibody, gap junction protein gamma 3 antibody, LOC100349037 antibody, Gjc3 antibody, GJC3 antibody

Background:

Synonyms: Connexin 29, connexin29, connexin-29, Connexin 30.2, Connexin 31.3, Connexin-30.2, Connexin-31.3, CX23, Cx29 , Cx30.2, Cx31.3, CXG3_HUMAN, Gap junction epsilon 1 protein, Gap junction epsilon-1 protein , Gap junction gamma 3 protein, Gap junction gamma-3 protein, Gap junction protein epsilon 1 29 kDa, Gap junction protein epsilon 1, Gap junction protein gamma 3 30.2 kDa, Gap junction protein gamma 3, GJC 3 antibodyGJC3, GJE 1.

Background: Connexin 29 belongs to the connexin family and is a member of the epsilon-type subfamily. Connexin 29 is a membrane bound, multi-pass protein also known as gap junction epsilon-1 protein. A connexon, consisting of connexin hexamers, is a membrane bound structure that is integral in the formation of a gap junction. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Connexin 29 expression is restricted to the central nervous system and is present in brain, spinal cord, and sciatic nerve samples. It has been suggested that connexin 29 in the mature CNS contributes minimally to gap junctional intercellular communication in oligodendrocyte cell bodies. Rather, connexin 29 is targeted to myelin where it, along with connexin 32, may contribute to connexin-mediated communication between adjacent layers of uncompacted myelin.

Pathways: Sensory Perception of Sound