DCAF13 antibody

Catalog No. ABIN1385659

Product Details anti-DCAF13 Antibody

Target: DCAF13 (DDB1 and CUL4 Associated Factor 13 (DCAF13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCAF13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DCAF13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DCAF13

Target: DCAF13 (DDB1 and CUL4 Associated Factor 13 (DCAF13))

Alternative Name: DCAF13 (DCAF13 Products)

Synonyms: wdsof1 antibody, WDSOF1 antibody, GM83 antibody, Gm83 antibody, Wdsof1 antibody, zgc:55391 antibody, DDB1 and CUL4 associated factor 13 antibody, DDB1 and CUL4 associated factor 13 L homeolog antibody, ddb1 and cul4 associated factor 13 antibody, dcaf13 antibody, DCAF13 antibody, Dcaf13 antibody, dcaf13.L antibody

Background:

Synonyms: DCA13_HUMAN, DCAF13, DDB1 and CUL4 associated factor 13, DDB1- and CUL4-associated factor 13, DKFZP564O0463, GM83, HSPC064, WD repeat and SOF domain-containing protein 1, WD repeats and SOF1 domain containing, WDSOF1.

Background: Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.