RTP3 antibody (AA 21-120)

Catalog No. ABIN1385626

Product Details anti-RTP3 Antibody

Target: RTP3 (Receptor (Chemosensory) Transporter Protein 3 (RTP3))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RTP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RTP3

Target: RTP3 (Receptor (Chemosensory) Transporter Protein 3 (RTP3))

Alternative Name: RTP3 (RTP3 Products)

Synonyms: Tmem7 antibody, LTM1 antibody, TMEM7 antibody, receptor (chemosensory) transporter protein 3 antibody, receptor transporter protein 3 antibody, Rtp3 antibody, RTP3 antibody

Background:

Synonyms: LTM1, Receptor chemosensory transporter protein 3, Receptor transporter protein 3, Receptor-transporting protein 3, RTP3, RTP3_HUMAN, TMEM7, Transmembrane protein 7.

Background: Members of the RTP (receptor transporter proteins) family have recently been discovered to influence bitter taste receptor expression in addition to inducing the expression of mammalian odorant receptors. RTP3 is a 232 amino acid single-pass type III membrane protein belonging to the TMEM7 family. Unlike other RTP proteins, RTP3 is not expressed in olfactory neurons but is expressed predominantly in liver. RTP3 is involved in the functional expression of bitter taste receptors and suppresses cell proliferation, and is also found in human circumvallate papillae and testis (regions where bitter taste receptors are expressed). The gene encoding RTP3 maps to human chromosome 3p21.31 within C3CER1 (chromosome 3 common eliminated region 1), which is frequently eliminated in chromosomal deletions of solid tumors.