DENND2C antibody

Catalog No. ABIN1385606

Product Details anti-DENND2C Antibody

Target: DENND2C (DENN/MADD Domain Containing 2C (DENND2C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND2C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DENND2C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DENND2C

Target: DENND2C (DENN/MADD Domain Containing 2C (DENND2C))

Alternative Name: DENND2C (DENND2C Products)

Synonyms: si:dkeyp-46c9.6 antibody, MGC145874 antibody, dJ1156J9.1 antibody, A930010I20Rik antibody, RGD1308197 antibody, DENN domain containing 2C antibody, DENN/MADD domain containing 2C antibody, DENND2C antibody, dennd2c antibody, Dennd2c antibody

Background:

Synonyms: DENN/MADD domain containing 2C, dJ1156J9.1, DKFZp686G0351, DKFZp686N1631, DKFZp779P1149, FLJ37099, RP5-1156J9.1, DEN2C_HUMAN.

Background: DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8 % of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.

Gene ID: 163259