C12ORF24 antibody (AA 195-245)

Catalog No. ABIN1385538

Product Details anti-C12ORF24 Antibody

Target: C12ORF24 (C12orf24) (Chromosome 12 Open Reading Frame 24 (C12orf24))

Binding Specificity: AA 195-245

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C12ORF24 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C12ORF24

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C12ORF24

Target: C12ORF24 (C12orf24) (Chromosome 12 Open Reading Frame 24 (C12orf24))

Alternative Name: C12ORF24 (C12orf24 Products)

Synonyms: C12orf24 antibody, C17H12orf24 antibody, HSU79274 antibody, 1500011H22Rik antibody, family with sequence similarity 216 member A antibody, family with sequence similarity 216, member A antibody, FAM216A antibody, Fam216a antibody

Background:

Synonyms: Chromosome 12 open reading frame 24, HSU79274, Hypothetical protein LOC29902, Protein predicted by clone 23733, F216A_HUMAN, Protein FAM216A, FAM216A.

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf24 gene product has been provisionally designated C12orf24 pending further characterization.

Gene ID: 29902

UniProt: Q8WUB2