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MYLK3 antibody

MYLK3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385505
  • Target See all MYLK3 Antibodies
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Reactivity
    • 49
    • 34
    • 17
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 58
    Rabbit
    Clonality
    • 58
    Polyclonal
    Conjugate
    • 18
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYLK3 antibody is un-conjugated
    Application
    • 48
    • 28
    • 25
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYLK3
    Isotype
    IgG
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    Discover our top product MYLK3 Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Alternative Name
    MYLK3 (MYLK3 Products)
    Synonyms
    MLCK antibody, MLCK2 antibody, caMLCK antibody, D830007F02Rik antibody, RGD1305801 antibody, myosin light chain kinase 3 antibody, MYLK3 antibody, Mylk3 antibody
    Background

    Synonyms: caMLCK, Cardiac MyBP C associated Ca/CaM kinase, Cardiac-MyBP-C-associated Ca/CaM kinase, MLC kinase, MLCK, MLCK2, Mylk3, MYLK3_HUMAN, Myosin light chain kinase 3, Putative myosin light chain kinase 3.

    Background: The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

    Pathways
    Regulation of Muscle Cell Differentiation
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