TRABD2A antibody
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- Target See all TRABD2A products
- TRABD2A (TraB Domain Containing 2A (TRABD2A))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRABD2A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human C2orf89
- Isotype
- IgG
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anti-TraB Domain Containing 2A (TRABD2A) (AA 342-371), (C-Term) antibody
TRABD2A Reactivity: Human WB Host: Rabbit Polyclonal RB29636 unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- TRABD2A (TraB Domain Containing 2A (TRABD2A))
- Alternative Name
- C2orf89 (TRABD2A Products)
- Synonyms
- C2orf89 antibody, TIKI1 antibody, TraB domain containing 2A antibody, TRABD2A antibody
- Background
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Synonyms: C2orf89, CB089_HUMAN, UPF0632 protein C2orf89.
Background: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [COFACTOR] Divalent metal cations. Manganese or cobalt.
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