C19orf28 antibody

Catalog No. ABIN1385462

Product Details anti-C19orf28 Antibody

Target: C19orf28 (Chromosome 19 Open Reading Frame 28 (C19orf28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C19orf28 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MFSD12/C19orf28

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C19orf28

Target: C19orf28 (Chromosome 19 Open Reading Frame 28 (C19orf28))

Alternative Name: C19orf28 (C19orf28 Products)

Synonyms: MGC81076 antibody, C19orf28 antibody, PP3501 antibody, F630110N24Rik antibody, Wdt1 antibody, major facilitator superfamily domain containing 12 L homeolog antibody, major facilitator superfamily domain containing 12 antibody, mfsd12.L antibody, mfsd12 antibody, MFSD12 antibody, Mfsd12 antibody

Background:

Synonyms: Chromosome 19 open reading frame 28, Hypothetical protein LOC126321, MGC20700, PP3501, Uncharacterized MFS type transporter C19orf28, MFS12_HUMAN.

Background: C19orf28, also known as PP3501, is a multi-pass membrane protein that belongs to the major facilitator superfamily. The gene encoding C19orf28 localizes to chromosome 19 and, due to alternative splicing events, C19orf28 exists as two isoforms. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2 % of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The C19orf28 gene product has been provisionally designated C19orf28 pending further characterization.