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C18orf1 antibody (AA 1-50)

C18orf1 Reactivity: Human, Mouse, Rat WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385453
  • Target See all C18orf1 Antibodies
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 1-50
    Reactivity
    • 22
    • 20
    • 20
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 2
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C18orf1 antibody is un-conjugated
    Application
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C18orf1
    Isotype
    IgG
    Top Product
    Discover our top product C18orf1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Alternative Name
    C18orf1 (C18orf1 Products)
    Synonyms
    C18orf1 antibody, 8230401C20Rik antibody, A430083H02 antibody, A430108L08Rik antibody, D18Ertd653e antibody, D330030L18Rik antibody, low density lipoprotein receptor class A domain containing 4 antibody, LDLRAD4 antibody, Ldlrad4 antibody
    Background

    Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4

    Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

    Gene ID
    753
    UniProt
    O15165
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