C6ORF1 antibody

Catalog No. ABIN1385426

Product Details anti-C6ORF1 Antibody

Target: C6ORF1 (Chromosome 6 Open Reading Frame 1 (C6ORF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C6ORF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C6ORF1

Target: C6ORF1 (Chromosome 6 Open Reading Frame 1 (C6ORF1))

Alternative Name: C6orf1 (C6ORF1 Products)

Synonyms: LBH antibody, small integral membrane protein 29 antibody, SMIM29 antibody

Background:

Synonyms: C6orf1, CF001_HUMAN, Chromosome 6 open reading frame 1, Hypothetical protein LOC221491, LBH, MGC57858, Protein LBH, Uncharacterized protein C6orf1.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf1 gene product has been provisionally designated C6orf1 pending further characterization.

Gene ID: 221491