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LRRC59 antibody (AA 21-120)

LRRC59 Reactivity: Mouse, Rat WB, IHC (p), ELISA, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385303
  • Target See all LRRC59 Antibodies
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reactivity
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 13
    Rabbit
    Clonality
    • 13
    Polyclonal
    Conjugate
    • 13
    This LRRC59 antibody is un-conjugated
    Application
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LRRC59
    Isotype
    IgG
    Top Product
    Discover our top product LRRC59 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    Alternative Name
    LRRC59 (LRRC59 Products)
    Synonyms
    p34 antibody, PRO1855 antibody, AA959742 antibody, C78668 antibody, leucine rich repeat containing 59 antibody, leucine rich repeat containing 59 S homeolog antibody, LRRC59 antibody, Lrrc59 antibody, lrrc59.S antibody
    Background

    Synonyms: Leucine-rich repeat-containing protein 59, LRC59_HUMAN, LRRC59, PRO1855.

    Background: LRRC59 (leucine rich repeat containing 59), also known as PRO1855, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell. The gene encoding LRRC59 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Gene ID
    55379
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