ACCN5 antibody (AA 231-350)

Catalog No. ABIN1385229

Product Details anti-ACCN5 Antibody

Target: ACCN5 (Amiloride-Sensitive Cation Channel 5, Intestinal (ACCN5))

Binding Specificity: AA 231-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACCN5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ACCN5

Target: ACCN5 (Amiloride-Sensitive Cation Channel 5, Intestinal (ACCN5))

Alternative Name: ACCN5 (ACCN5 Products)

Synonyms: ACCN5 antibody, HINAC antibody, INAC antibody, Accn5 antibody, Blinac antibody, Inac antibody, acid sensing ion channel subunit family member 5 antibody, acid-sensing (proton-gated) ion channel family member 5 antibody, ASIC5 antibody, asic5 antibody, Asic5 antibody

Background:

Synonyms: amiloride sensitive cation channel 5, intestinal, Amiloride sensitive sodium channel,intestine Na+ channel, amiloride-sensitive cation channel 5, HINAC, INAC, ASIC5_HUMAN.

Background: ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride.