TMEM176B antibody (AA 25-150)

Catalog No. ABIN1385213

Product Details anti-TMEM176B Antibody

Target: TMEM176B (Transmembrane Protein 176B (TMEM176B))

Binding Specificity: AA 25-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM176B antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LR8/TMEM176B

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TMEM176B

Target: TMEM176B (Transmembrane Protein 176B (TMEM176B))

Alternative Name: LR8/TMEM176B (TMEM176B Products)

Synonyms: MGC165671 antibody, LR8 antibody, 1810009M01Rik antibody, Clast1 antibody, Lr8 antibody, Torid antibody, transmembrane protein 176B antibody, TMEM176B antibody, Tmem176b antibody

Background:

Synonyms: LR 8, TMEM176B, Transmembrane protein 176B, T176B_HUMAN.

Background: Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The LR8 gene product has been provisionally designated LR8 pending further characterization.