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ZBTB17 antibody (AA 331-430)

ZBTB17 Reactivity: Mouse WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385184
  • Target See all ZBTB17 Antibodies
    ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
    Binding Specificity
    • 14
    • 14
    • 8
    • 1
    • 1
    AA 331-430
    Reactivity
    • 24
    • 24
    • 9
    Mouse
    Host
    • 39
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZBTB17 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Miz1/ZNF60
    Isotype
    IgG
    Top Product
    Discover our top product ZBTB17 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Liu, Lai, Zhao, Chen: "Increased expression of Myc-interacting zinc finger protein 1 in APP/PS1 mice." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5751-5756, (2017) (PubMed).

  • Target
    ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
    Alternative Name
    Miz1/ZNF60 (ZBTB17 Products)
    Synonyms
    MIZ-1 antibody, ZNF151 antibody, ZNF60 antibody, pHZ-67 antibody, AA589413 antibody, Lp-1 antibody, Miz1 antibody, Zfp100 antibody, mZ13 antibody, Miz-1 antibody, zbtb17 antibody, zinc finger and BTB domain containing 17 antibody, zinc finger and BTB domain containing 17 S homeolog antibody, ZBTB17 antibody, Zbtb17 antibody, zbtb17.S antibody
    Background

    Synonyms: Miz-1, Myc-interacting zinc finger protein 1, Myc-interacting zinc finger protein, ZBT17, ZBT17_HUMAN, Zbtb17, Zinc finger and BTB domain containing protein 17, Zinc finger and BTB domain-containing protein 17, Zinc finger protein 151, Zinc finger protein 60, ZNF151, ZNF60.

    Background: The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.

    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
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