FAM71D antibody (AA 1-100)

Catalog No. ABIN1385142

Product Details anti-FAM71D Antibody

Target: FAM71D (Family with Sequence Similarity 71, Member D (FAM71D))

Binding Specificity: AA 1-100

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM71D antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM71A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FAM71D

Target: FAM71D (Family with Sequence Similarity 71, Member D (FAM71D))

Alternative Name: FAM71D (FAM71D Products)

Synonyms: GARI-L2 antibody, 4921509E07Rik antibody, 4930516C23Rik antibody, C14orf54 antibody, C10H14orf54 antibody, family with sequence similarity 71, member D antibody, family with sequence similarity 71 member D antibody, Fam71d antibody, FAM71D antibody

Background:

Synonyms: C14orf54, Chromosome 14 open reading frame 54, Family with sequence similarity 71, member D, FLJ36130, GARI-L2, Golgi-associated Rab2B interactor-like 2, Hypothetical protein LOC161142, Protein FAM71D, FA71D_HUMAN.

Background: Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14,19) translocations found in a variety of B cell malignancies. The FAM71D gene product has been provisionally designated FAM71D pending further characterization.

Gene ID: 149647