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CD74 antibody (Biotin)

CD74 Reactivity: Human FACS Host: Mouse Monoclonal LN2 Biotin
Catalog No. ABIN135827
  • Target See all CD74 Antibodies
    CD74 (HLA-DR-gamma (CD74))
    Reactivity
    • 178
    • 67
    • 13
    • 10
    Human
    Host
    • 117
    • 82
    • 3
    • 2
    Mouse
    Clonality
    • 133
    • 69
    • 2
    Monoclonal
    Conjugate
    • 68
    • 15
    • 15
    • 9
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    • 7
    • 5
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This CD74 antibody is conjugated to Biotin
    Application
    • 122
    • 109
    • 78
    • 40
    • 34
    • 34
    • 29
    • 26
    • 16
    • 14
    • 13
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    • 1
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    Flow Cytometry (FACS)
    Specificity
    Human CD74, Mr 41, 35, 33 kDa
    Characteristics
    Mouse Anti-Human CD74-BIOT
    Purification
    Ion exchange column
    Immunogen
    Cell line SU-DHL-4 nuclei
    Clone
    LN2
    Isotype
    IgG1
    Top Product
    Discover our top product CD74 Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Restrictions
    For Research Use only
  • Buffer
    100 tests in 1.0 mL of PBS/Sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD74 (HLA-DR-gamma (CD74))
    Alternative Name
    CD74 (CD74 Products)
    Background
    CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface.
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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