CD79B
Reactivity: Human
FACS
Host: Mouse
Monoclonal
CB3-1
APC
Application Notes
Applications: FC - Quality tested , IP - Reported in literature , WB - Reported in literature
Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
Restrictions
For Research Use only
Buffer
100 tests in 1.0 mL of PBS/Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect conjugated products from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
CD79 is a 23/21 disulfide-linked heterodimer composed of an chain (CD79a/mb-1) and a chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation.