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CD51 antibody (PE)

ITGAV Reactivity: Human IHC, FACS Host: Mouse Monoclonal 13C2 PE
Catalog No. ABIN135793
  • Target See all CD51 (ITGAV) Antibodies
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reactivity
    • 93
    • 52
    • 23
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 65
    • 29
    • 9
    Mouse
    Clonality
    • 58
    • 44
    Monoclonal
    Conjugate
    • 55
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51 antibody is conjugated to PE
    Application
    • 48
    • 45
    • 29
    • 26
    • 21
    • 14
    • 14
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Specificity
    Human/African Green Monkey/Rabbit/Bovine CD51, Mr 125 & 24 kDa
    Characteristics
    Mouse Anti-Human CD51-PE
    Immunogen
    Cell suspension containing osteoclasts from osteoclastomas
    Clone
    13C2
    Isotype
    IgG1
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  • Application Notes
    Working Dilution:
    FACS: 10 µL/10^6 cells
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    Restrictions
    For Research Use only
  • Buffer
    Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
    Handling Advice
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Alternative Name
    CD51 (ITGAV Products)
    Synonyms
    1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
    Background
    CD51 represents the 150 kDa integrin V chain that associates with integrin 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit, it can form heterodimers with the 1 (CD29), 3 (CD61), 5, 6 and 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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