CD51 antibody (PE)
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD51 antibody is conjugated to PE
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Specificity
- Human/African Green Monkey/Rabbit/Bovine CD51, Mr 125 & 24 kDa
- Characteristics
- Mouse Anti-Human CD51-PE
- Immunogen
- Cell suspension containing osteoclasts from osteoclastomas
- Clone
- 13C2
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV Primary Antibody
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- Application Notes
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Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. - Restrictions
- For Research Use only
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- Buffer
- Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
- Handling Advice
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- CD51 (ITGAV Products)
- Synonyms
- 1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
- Background
- CD51 represents the 150 kDa integrin V chain that associates with integrin 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit, it can form heterodimers with the 1 (CD29), 3 (CD61), 5, 6 and 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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