CD4 antibody
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- Target See all CD4 Antibodies
- CD4
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- Human CD4, Mr 55 kDa
- Characteristics
- Mouse Anti-Human CD4-LE/AF
- Endotoxin Level
- Low endotoxin
- Immunogen
- Thymocyte and E-rosetted lymphocytes
- Clone
- RFT4
- Isotype
- IgG1
- Top Product
- Discover our top product CD4 Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , Sep - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, PE/TXRD, APC, SPRD, CY5, PE/CY5.5, 10 L/106 cells PE/CY7, APC/CY7, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Sample Volume
- 0,2 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Preservative
- Azide free
- Handling Advice
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Storage
- -20 °C
- Storage Comment
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Target
- CD4
- Alternative Name
- CD4 (CD4 Products)
- Synonyms
- cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
- Background
- D4 is a 59 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the helper/inducer subpopulation of mature T lymphocytes, and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessary molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells.
- Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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