ChT antibody (FITC)
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- Target See all ChT Antibodies
- ChT (High Affinity Choline Transporter (ChT))
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Reactivity
- Chicken
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ChT antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Specificity
- Chicken/Quail ChT1, Mr 63 & 103 kDa
- Characteristics
- Mouse Anti-Chicken ChT1-FITC
- Immunogen
- Chicken thymocytes
- Clone
- CT1
- Isotype
- IgG1
- Top Product
- Discover our top product ChT Primary Antibody
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- Application Notes
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- Applications: FC - Quality tested , IP - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Comment
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In vitro inhibition of T cell differentiation
- Sample Volume
- 1 mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 0.5 mg in 1.0 mL of PBS/Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Storage
- 4 °C
- Storage Comment
- Store at 2-8°C
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- Target
- ChT (High Affinity Choline Transporter (ChT))
- Alternative Name
- ChT1 (ChT Products)
- Synonyms
- CHT antibody, CHT1 antibody, HMN7A antibody, hCHT antibody, Cht1 antibody, solute carrier family 5 member 7 antibody, solute carrier family 5 (choline transporter), member 7 antibody, SLC5A7 antibody, Slc5a7 antibody
- Background
- ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90 % of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive. Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. CT1 also recognizes quail cortical thymocytes.
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